CAP (catabolite activator protein):
A protein, which binds cyclic AMP, whose presence is necessary for the activation of operons whose activity is repressed by the presence of glucose (catabolite repression) eg. lac (lactose), ara (arabinose), gal (galactose) etc. cAMP-CAP complex binds to a site, the CAP binding site, which is centred at -61 to -62 from the transcription start site in the lac operon promoter.
|